Endotoxin-induced Abortion in Early Pregnant Gilts and its Prevention by Flunixin Meglumine
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Toxicity of Flunixin Meglumine in Broiler Chickens
This study was designed to evaluate the toxicity of flunixin meglumine, a nonsteroidal anti-inflammatory drug which might serve as an alternate of diclofenac that has been shown to cause toxicity in vultures. Twenty five broiler chickens of five weeks of age were randomly divided into five equal groups and treated with flunixin meglumine at the dosage rate of 0, 1.25, 2.5, 5 and 10 mg/kg body w...
متن کاملPharmacokinetic interactions of flunixin meglumine and enrofloxacin in ICR mice.
We examined the pharmacokinetic interactions of enrofloxacin and flunixin in male ICR mice that were subcutaneously (SC) administered with both or either one of the drugs. The experiments were performed on the following three groups: flunixin alone (2 mg/kg, SC), combination of flunixin (2 mg/kg, SC) and enrofloxacin (10 mg/kg, SC), and enrofloxacin alone (10 mg/kg, SC). Blood samples were coll...
متن کاملAvoiding violative flunixin meglumine residues in cattle and swine.
JAVMA • Vol 250 • No. 2 • January 15, 2017 Flunixin meglumine is an NSAID that is approved by the FDA for the treatment of inflammatory conditions in cattle, horses, and swine and alleviation of pain associated with musculoskeletal disorders and colic in horses; it is not labeled for alleviation of pain in food-producing animals. Currently, there are no FDAapproved drugs for the treatment of py...
متن کاملEffect of intracerebroventricular injection of flunixin meglumine on PTZ-induced seizures in male rats
Introduction: Flunixin Meglumine (FM) is a nonsteroidal antiinflammatory drug (NSAID) and nonselective cyclooxygenase (COX) inhibitor. Since it has been suggested that COX enzyme plays a role in seizure, this research is performed to assess the therapeutic effects that this compound might have in seizures induced by PTZ. Methods: In this research, male wistar rats (200 ± 20 g) were given int...
متن کاملEffects of flunixin meglumine on pregnancy establishment in beef cattle.
The objective of this research was to determine effects of a single injection of the PG synthesis inhibitor flunixin meglumine (FM; 1.1 mg/kg of BW, intramuscularly) approximately 13 d (range 10 to 15 d) after AI on pregnancy establishment. Three experiments were conducted using estrus-synchronized heifers and cows. Technicians and AI sires were equally represented across treatments within loca...
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ژورنال
عنوان ژورنال: Acta Veterinaria Scandinavica
سال: 1990
ISSN: 1751-0147
DOI: 10.1186/bf03547547